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© The Canadian Journal of Urology™; 23(Supplement 1); February 2016

Gender differences in overactive bladder

Renu S. Eapen, MD, Sidney B. Radomski, MD

Division of Urology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada

EAPEN RS, RADOMSKI SB. Gender differences in

overactive bladder.

Can J Urol

2016;23(Suppl 1):2-9.

Overactive bladder (OAB) is a common condition in both

women and men. Although prevalence’s are similar in

both genders, sex specific differences do exist in relation to

individual OAB symptoms as well as degree of bother and

quality of life. The added effect of prostatic enlargement

in men leads to slightly different evaluation and treatment

regimens in both genders. This review will examine the

gender differences in OAB related to epidemiology, OAB

evaluation, investigation and treatment. This information

will assist the primary care physician in assessing and

initiating treatment in patients with OAB. It will further

the understanding of the spectrum of treatments available

for OAB and assist in determining the appropriateness

and timing of referral of such patients to a urologist.

Key Words:

OAB, overactive bladder, BPH, benign

prostatic hyperplasia

impact on overall quality of life, sexual function, sleep

and mental health in both genders. According to the

International Continence Society (ICS) definition,

OAB consists of urinary urgency with or without urge

incontinence (UI), often accompanied by frequency

and nocturia. The urodynamic characteristic of OAB

is detrusor overactivity (DO). Many publications

have studied the prevalence of OAB in developed

2

Introduction

Overactive bladder (OAB) is a prevalent condition

in both men and women. It can have a significant

Address correspondence toDr. Sidney B. Radomski, Division

of Urology, Toronto Western Hospital, 399 Bathurst Street,

MP8-304, Toronto, ON M5T 2S8 Canada