Abstract

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• Urodynamic pressure-flow studies provide an objective means of identifying bladder outlet obstruction. However, standard tests are invasive. This study evaluates a non-invasive method of obtaining pressure-flow data. One hundred men without clinical evidence of urinary obstruction were divided into 5 age groups. Non-invasive "cuff flow" urodynamic studies were obtained in each subject. Initial Pressure (P), initial flow (Q), resistive indices (Req =P/Q²) and uroflow patterns were obtained. With increasing age there were higher detrusor pressures, slower flows and greater resistive indices. This is in accordance with the prevalence of asymptomatic bladder outlet obstruction in older men. Statistical analysis revealed that Req is a highly reproducible value. An age specific nomogram for clinically unobstructed men was developed. The cuff flow devices is a new and reliable means of obtaining pressure-flow data in a non-invasive manner. From the values of Req in normal unobstructed men, future trials will assess clinically obstructed subjects prior to and after treatment.