Welcome to the CJU website » LOG IN


Complete pathologic response of bulbar urethral squamous cell carcinoma in situ to topical 5-fluorouracil with urethral milking
Department of Urology, Mayo Clinic Florida, Jacksonville, Florida, USA
Apr  2022 (Vol.  29, Issue  2, Pages( 11119 - 11122)
PMID: 35429432


Text-Size + 

  • Primary urethral carcinoma is a rare oncologic condition with limited data to support organ-sparing therapies. Herein, we present a case of primary urethral squamous cell carcinoma in situ of the bulbar urethra treated with intraurethral 5-fluorouracil (5-FU) who exhibited a complete pathologic response observed at the time of dismembered urethroplasty. The clinical features, diagnosis, and treatment course of our case are reviewed. These data may support the use of intraurethral 5-FU for similar cases in the future.