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Penoscrotal lymphedema associated with metastatic renal cell carcinoma
Urology Division, Hartford Healthcare Medical Group, Hartford, Connecticut, USA
Aug  2015 (Vol.  22, Issue  4, Pages( 7932 - 7934)
PMID: 26267035


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  • A 64-year-old male presented with lower back pain, radiating in a sciatic-type distribution, swelling in his lower abdomen and right leg, and edema of the scrotum and penile shaft. A sonogram and CT imaging indicated an enhancing mass in the right kidney and a spinal metastasis. The right lower extremity and penoscrotal lymphedema was caused by lymphatic obstruction due to a sacral metastasis of renal cell carcinoma. He was treated with cytoreductive nephrectomy, radiation and a systemic tyrosine kinase inhibitor. Pelvic imaging is suggested to determine whether malignant lymphatic obstruction is present when presented with idiopathic penoscrotal edema.