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An integral view of the neuroendocrine aspects of male sexual dysfunction and aging
Department of Urology, Kingston General Hospital, Queen's University, Kings
Apr  2003 (Vol.  10, Issue  2, Pages( 1777 - 1779)


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  • Age is the most important factor associated with sexual dysfunction. The traditional thinking explained this association by the neurovascular events developing with the aging process. More recently, central neuro-endocrine mechanisms resulting from apoptosis in the hypothalamic areas involved in both the production of sex hormones and the control of sexual processes have added a new dimension to human sexuality. This evidence is still controversial but of unquestionable importance in our understanding of endocrine alterations and sexual shortcomings associated with aging.