Laparoscopic radical nephrectomy has gained acceptance as a viable means of managing renal neoplasms. Partial nephrectomy has traditionally been performed through a flank or transabdominal incision, with its attendant morbidity and required hospitalization. Laparoscopic renal-sparing surgery may be more technically demanding, but remains beneficial to the patient if performed with adherence to oncological principles. We present a case of laparoscopic renal-sparing surgery in a patient with a renal mass in a solitary kidney. We discuss the technical and oncological challenges of this approach.