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Hand, foot, and mouth disease presenting with a testicular mass in an adult
Department of Urology, George Washington University, Washington, DC, USA
Apr  2024 (Vol.  31, Issue  2, Pages( 11854 - 11857)
PMID: 38642464


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  • The majority of solid testicular tumors are treated with orchiectomy given the high risk of malignancy. We present a case of a testicular mass in an adult patient in the setting of recent hand, foot, and mouth disease that was managed conservatively with serial ultrasounds. Even though cases of viral-associated testicular masses are rare, this differential diagnosis should be considered in patients with a new testicular mass in the setting of recent viral infection and negative tumor markers. For these patients, observation may be an option instead of immediate orchiectomy.