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Aggressive prostate cancer masquerading as acute prostatitis
Division of Urology, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA
Aug  2021 (Vol.  28, Issue  4, Pages( 10799 - 10801)
PMID: 34378519


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  • Prostatitis is a common cause of prostate-specific antigen (PSA) elevation but can masquerade underlying prostate cancer. We present a case of a man with undiagnosed prostate cancer whose initial PSA elevation of > 999.0 ng/mL was initially ascribed entirely to prostatitis. In the setting of possible prostatitis clinicians should avoid the knee jerk reaction to blame the totality of PSA elevation on prostatitis. A greatly elevated PSA may be a sign of an underlying prostate cancer and should be explored in the proper clinical setting.