Content

Welcome to the CJU website » LOG IN

Details

Germline testing for prostate cancer prognosis: implications for active surveillance
Program for Personalized Cancer Care and Division of Urology, NorthShore University HealthSystem, Evanston, Illinois, USA
Oct 2019 (Vol. 26, Issue 52, Pages( 48 - 49)
PMID: 31629432

Abstract

Text-Size + 

  • Based upon an evidence-based review of recently published manuscripts including our own studies, we first review germline variants that are significantly associated with prostate cancer aggressiveness and progression. We then discuss the clinical implication of germline variants in predicting grade reclassification of prostate cancer patients undergoing active surveillance. Finally, based on currently available evidence, we propose a working recommendation of germline testing and corresponding clinical management for localized prostate cancer patients, including those undergoing active surveillance.

Current Issue

August 2020, Vol.27 No.4
canadian journal of urology