Abstract

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• Studies have repeatedly confirmed that about 52% of men between the ages of 40 and 70 years have some degree of erectile dysfunction (ED). Other studies have shown that as a man ages, his testosterone level will naturally decrease. Over the last number of years, we have also seen that ED may be one of the earliest signs and markers of endothelial dysfunction. There appears to be an overlap between ED, metabolic syndrome, and symptomatic late onset hypogonadism (SLOH). It is very important for the primary care physician to identify patients who are suffering from ED and/or hypogonadism, and to also identify any other existing comorbidities. This article discusses the suggested work up, diagnosis, and management of men who present with either ED or symptoms and signs suggestive of hypogonadism (low testosterone). It also discusses the potential relationship between these conditions and metabolic syndrome.