Page 58 - Urology Update for Primary Care Physicians for 2013

© The Canadian Journal of Urology™; 19(Supplement 1); October 2012
References
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47
Diagnosis and management of simple and complicated urinary tract infections (UTIs)
is lacking.
7
One preventative strategy that has been
greatly debated has been the effectiveness of cranberry-
containing products for the prevention of UTIs. Arecent
systematic review and meta-analysis of randomized
controlled trials of cranberry-containing products
concluded that their use is associated with a protective
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45
The investigators cautioned that the results should be
interpreted in the context of substantial heterogeneity
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provides an alternative (or addition) to the use of
low-dose antimicrobial prophylaxis for women with
recurrent UTIs.
Summary
UTIs remain a common clinical problem in both the
community and healthcare-associated settings. Each
patient should be carefully assessed to ensure that
a correct diagnosis is made and that antimicrobial
therapy is appropriately prescribed—defined as using
a clinically indicated agent in the correct dose and
route of administration, for the correct duration—
for symptomatic patients, and avoided for most
asymptomatic patients. This should help stem the
growing tide of antimicrobial resistance and allow for
the continued use of simpler, less expensive agents.
Continued surveillance andmonitoring of antimicrobial
resistance rates will be critical to help formulate and
update future treatment recommendations for all
categories of patients with UTIs.
Disclosure
Dr. Tony Mazzulli has been a member of scientific
advisoryboards,receivedresearchgrantsand/orspeaker
honoraria from the following commercial entities:
Bayer Healthcare, Pfizer, Merck Frosst, Luminex, and
Gilead.
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