Abstracts from the Abstracts from the Mid-Atlantic Section of the AUA 2021

MA-AUA 2021 Abstracts Moderated Poster Session 3: BPH/Urodynamics MP3-08 Stress Incontinence Outcomes Following Robotic Prostatectomy: Interim Analysis of Novel Pelvic Floor Program J. Farhi, D. Barquin, A. DeNovio, D. Rapp University of Virginia, Charlottesville, VA, USA Introduction and Objective: The AUA Guideline for incontinence after prostate treatment recommends that clinicians offer pelvic floor muscle training (PFMT) in the immediate post-operative period. The UVA prostatectomy functional outcomes program (PFOP) was developed in 2018 to comprehensively assess and optimize continence outcomes following radical prostatectomy. Enrolled patients completed specialized in-house pelvic floor muscle training (PFMT) directed by a fellowship-trained FPMRS specialist. PFMT sessions were conducted at baseline, 3-months, 6-months, and 12-months following surgery andwere supplemented by a home exercise program. Methods: We performed an interim analysis of 14 PFOP patients achieving 6-month follow-up after robotic prostatectomy. As part of ongoing prospective assessment, patients complete the validated ICIQ-MLUTS and IIQ-7 questionnaires. Comparison of questionnaire items focused on SUI and QOL was performed and compared to 18 non-PFOP patients undergoing prostatectomy. Non-PFOP patients received standard PFMT education provided by their treating urologic oncologist. Results: Mean patient age, EBL, proportion of patients undergoing adjuvant radiotherapy, pelvic lymph node dissection, and baseline SUI domain scores were similar in the PFOP versus non-PFOP cohorts (p=NS, all comparisons). ICIQ-MLUTS SUI domain items scores across all time points are shown in Figure 1. At 6-month follow-up, men enrolled in PFOP demonstrated significantly improved domain scores when compared to controls (PFOP 0.85 (SD 1.12); non-PFOP 1.72 (SD 1.53))(p<0.05). A higher proportion of PFOP patients reported absence of incontinence, defined as SUI domain score of 0 (PFOP 7/14 (50%); non-PFOP 5/18 (28%)). Similar pad per day quantity was reported across the cohorts. Conclusions: Specialized in-house PFMT performed by a fellowship-trained physician is associated with improved SUI outcomes and quality of life at 6-month follow-up. Patient accrual is ongoing tomore comprehensively assess continence outcomes with minimum 12-month follow-up. Relationship Between Overactive Bladder Symptom Severity and Cystometric Bladder Capacity in Patients with Overactive Bladder K. Lembrikova 1 , J. Blaivas 1,2 , J. Blaivas 3 1 SUNY Downstate, Brooklyn, NY, USA; 2 Icahn School of Medicine at Mount Sinai, NYC, NY, USA; 3 Institute for Prostate and Bladder Research, NYC, NY, USA Introduction andObjective: Severity of overactive bladder (OAB) symptoms is thought to be related to bladder capacity. The aim of this study is to test the hypotheses that OAB patients have low cystometric bladder capacities (CMBC), and an inverse relationship exists between symptom severity of OAB and CMBC. Methods: A database was searched for patients with lower urinary tract symptoms (LUTS) who had a 24-hour bladder diary, Overactive Bladder Symptom Score questionnaire (OABSS), videourodynamic study, uroflow, and post void residual urine. Patients were grouped based on OABSS: (1) OAB (with or without other LUTS) and (2) LUTS without OAB. Exclusion criteria were neurogenic bladder, UTI, and incomplete data. The relationship between OABSS and CMBC was calculated via Spearman’s nonparametric rank correlation coefficient andmean difference via independent sample t-test. Results: We identified 173 patients; 110 patients were included (mean age = 67). There were 67 women and 43 men; 66 had OAB and 44 had LUTS-only. Mean CMBC of OAB group was lower than LUTS-only (436 mL vs. 564 mL, t = 2, p = .05). Mean OABSS of OAB groupwas higher than LUTS-only (15 vs. 7, t = 11, p < .001). There was an inverse correlation between CMBC and OABSS. Half of the OAB group had a bladder capacity > 400 mL and 41% > 500mL. Conclusions: In this study of patients with LUTS, CMBCwas mostly normal, but lower than that of patients without OAB. Symptom severitywas inversely related to bladder capacity in OAB patients, but not in those without OAB. The observation that many patients with OAB had CMBC > 500 mL casts some doubt on the role of bladder capacity in the genesis of OAB symptoms. MP3-07 21